When you make your way to the Garage in Resident Evil Requiem, you’ll encounter the Organ Transport Box. Although it’s possible to interact with this item from your inventory, unlocking it requires you to follow a precise sequence outlined in a note obtained by solving the Lead Researcher’s Office puzzle.
If the diagram seems confusing, don’t worry! Below is a straightforward guide on how to successfully open the Organ Transport Box and understand its importance for advancing in Grace’s quest.
Unlocking the Organ Transport Box: A Step-by-Step Guide

The diagram for unlocking the Organ Transport Box provides critical information on the required actions and the specific order. If you’re having trouble deciphering it, follow these steps while inspecting the item in your inventory:
- Rotate the dial from the Auto position to the Hand position.
- Adjust the vertical slider to a middle position.
- Activate the fifth and second switches from the left.
- Finally, turn the dial from Hand back to Auto to unlock the box.
What Awaits Inside: The Reward

Upon successfully unlocking the box, you’ll find the vital Artificial Lungs. This item plays a crucial role in the ongoing narrative, especially in conjunction with the Artificial Heart you might have already acquired. Both the lungs and heart are necessary for your next steps in the Examination Room, where they must be used on the Organless Corpse to obtain another essential item.
This concludes our guide on unlocking the Organ Transport Box in Resident Evil Requiem.
This guide is based on a comprehensive playthrough completed on the Steam 1.0 version at Standard (Classic) difficulty. All images were captured from the same version.
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