
Overview
- Justin Hammer may return as a prominent antagonist in Captain America 5, seeking revenge.
- Sin, the daughter of Red Skull, could be pivotal in bringing Hydra back into the spotlight.
- Vermin, a tragic figure from the comics, might serve as a secondary antagonist, engrossing Captain America in his struggles.
The success of Captain America: Brave New World at the box office raises intriguing possibilities for Captain America 5. As one of the few Marvel Cinematic Universe (MCU) franchises to maintain consistent commercial appeal, it prompts speculation about the foes Sam Wilson will confront should Marvel Studios greenlight the sequel.
This next installment could introduce not only fresh supervillains from the comics but also characters from past MCU films and Disney+ series. With Brave New World wrapping up several long-running arcs, Captain America 5 may similarly resolve ongoing narratives.
1 Justin Hammer
War for the Iron Man Suits: The Return of Justin Hammer

- Debut in MCU: Iron Man 2
Following the reintroduction of Samuel Sterns as the primary antagonist in Brave New World, there’s a strong possibility that Justin Hammer could also make a comeback. After being thwarted by both Tony Stark and Ivan Vanko, Hammer’s desire for retribution could be fueled further with Iron Man’s death making Stark’s technology highly coveted.
While there were murmurs of Sam Rockwell reprising his role in the scrapped Armor Wars, Captain America 5 could present a new opportunity. Hammer could hatch a scheme to hijack Stark’s technology, potentially prompting Sam Wilson to ally with War Machine, Ironheart, or Rescue in the process.
2 Sin
Sin: A Catalyst for Hydra’s Return

- Comic Book Debut: Captain America Vol.1 #290
In the comic realm, Sin, the offspring of Red Skull, embodies ambition and seeks world domination, mirroring her father’s legacy. While the MCU has yet to confirm her existence, her character offers a robust narrative device to revive Hydra within the franchise.
Despite Hydra’s apparent defeat in previous films, remnants could linger. Introducing Sin not only provides an antagonist that aligns with the thematic elements of Captain America but also marks the entrance of a formidable female villain, paralleling Sam Wilson’s evolution as Captain America.
3 Vermin
Vermin: A Compelling Sub-Villain

- First Comic Appearance: Captain America Vol.1 #272
Within the Captain America narrative framework, a classic trope involves a secondary antagonist who complicates the hero’s journey.Vermin, equipped with a tragic backstory—transformed by Arnim Zola’s cruel experiments—emerges as an ideal candidate for this role.
This character, known for his rat-like appearance, embodies both horror and sympathy, allowing for thematic exploration of humanity during conflict. A potential confrontation between Sam Wilson and Vermin could highlight Wilson’s desire to redeem versus destroy, adding depth to the plot.
4 Sidewinder
A Request for More Sidewinder

- First MCU Appearance: Captain America: Brave New World
Despite having a brief stint in Brave New World, Sidewinder has the potential to develop into a central antagonist. Giancarlo Esposito has successfully portrayed his character’s allure, teasing a future encounter with Captain America.
Considering Sidewinder’s role as the leader of the Serpent Society in the comics, his reappearance could ignite a larger narrative arc, providing ample material for a sequel focused on this villainous group instead of merely a mercenary alliance.
5 Madame Hydra
Hydra’s Potential Renaissance

- First Comic Appearance: Captain America Vol.1 #110
While the MCU has explored various Hydra characters, including Red Skull and Zemo, Madame Hydra has yet to make her cinematic debut. With Hydra’s historical impact in the comics, her introduction would enrich the villain landscape, potentially juxtaposing with the Serpent Society.
Given Marvel Studios’ recent acquisition of character rights, blending Madame Hydra with Viper could yield exciting plotlines across various films, affirming her significance in the ongoing Captain America saga.
6 Power Broker
Sharon Carter: The Enigmatic Power Broker

- Debut in MCU: Captain America: The Winter Soldier
After her dramatic transformation revealed in The Falcon and The Winter Soldier, fans are eager to uncover Sharon Carter’s motives as the Power Broker. As a figure commanding a criminal empire in Madripoor, her role presents a morally complex character that could engage viewers.
Rumors suggest she could become embroiled in a renewed conflict with Hydra, potentially setting the stage for a war of factions with Sam Wilson caught in the middle. This narrative device allows for a deep exploration of trust and betrayal within the superhero genre.
7 Helmut Zemo
The Return of Baron Zemo

- First MCU Appearance: Captain America: Civil War
Helmut Zemo, portrayed expertly by Daniel Brühl, has emerged as one of the standout villains in the MCU. His return in The Falcon and The Winter Soldier further solidified his relevance, culminating in a richer character arc that aligns with comic lore, notably featuring his signature purple mask.
As the Avengers start to reunite and tensions shift regarding the Sokovia Accords, Zemo’s motivations could fuel further chaos. Speculating on the formation of a Masters of Evil team would provide a compelling setup for future storytelling opportunities.
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