
In the expansive world of Monster Hunter Wilds, crafting formidable weapons and durable armor is a crucial activity that requires an array of materials. One essential item you’ll need for creating the Rompopolo gear, as well as the armor sets for Rathian and Gypceros, is the Toxin Sac.
Toxin Sacs are obtained from specific monsters, containing potent toxins and powders that empower the impressive gear you will ultimately forge. Below, we’ll dive into the best locations to find Toxin Sacs in Monster Hunter Wilds.
Best Locations for Toxin Sacs
Toxin Sacs can be acquired by vanquishing two specific High Rank Large Monsters: Gypceros and Rompopolo. Gypceros roams areas like Windward Plains, Oilwell Basin, Iceshard Cliffs, and Ruins of Wyveria, while Rompopolo can predominantly be found in Oilwell Basin.

Keep in mind that obtaining Toxin Sacs is not guaranteed with each hunt. It may take several attempts to successfully secure the desired item.
Tips for Efficient Hunting
To optimize your chances of finding Toxin Sacs, start by consulting your World Map. Check the Environmental Overview on the right side of your screen to see if Gypceros or Rompopolo are currently present in their respective regions.
If you discover that the monsters aren’t available, consider resting at your Tent using Guild Points to refresh the spawn of these creatures. If you’d prefer to conserve your Guild Points, another effective strategy is to assist fellow Hunters by participating in their High Rank Gypceros or Rompopolo hunts through SOS Flare Quests.

To participate, access Alma’s Quest Menu and select ‘SOS Flare Quests’ from the menu’s bottom. Here, you can set filters to find quests that are available to join. Be sure to select High Rank, as Low Rank variations of Gypceros do not exist, and Low Rank Rompopolo drops Poison Sacs instead of Toxin Sacs.
After completing multiple hunts, you should accumulate enough Toxin Sacs to forge your desired weapons and armor pieces.
If you’re eager to learn more about Monster Hunter Wilds, check out our comprehensive tips and tricks. Additionally, discover our recommendations for the best weapons and how to catch a Sandstar.
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